DNA Molecular Storage System : Transferring Digitally Encoded Information through Bacterial Nanonetworks

Tavella, Federico and Giaretta, Alberto and Dooley-Cullinane, Triona Marie and Conti, Mauro and Coffey, Lee and Balasubramaniam, Sasitharan (2021) DNA Molecular Storage System : Transferring Digitally Encoded Information through Bacterial Nanonetworks. IEEE Transactions on Emerging Topics in Computing, 9 (3). pp. 1566-1580. ISSN 2168-6750

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Since the birth of computer and networks, fueled by pervasive computing, Internet of Things and ubiquitous connectivity, the amount of data stored and transmitted has exponentially grown through the years. Due to this demand, new storage solutions are needed. One promising media is the DNA as it provides numerous advantages, which includes the ability to store dense information while achieving long-term reliability. However, the question as to how the data can be retrieved from a DNA-based archive, still remains. In this paper, we aim to address this question by proposing a new storage solution that relies on bacterial nanonetworks properties. Our solution allows digitally-encoded DNA to be stored into motility-restricted bacteria, which compose an archival architecture of clusters, and to be later retrieved by engineered motile bacteria, whenever reading operations are needed. We conducted extensive simulations, in order to determine the reliability of data retrieval from motility-restricted storage clusters, placed spatially at different locations. Aiming to assess the feasibility of our solution, we have also conducted wet lab experiments that show how bacteria nanonetworks can effectively retrieve a simple message, such as 'Hello World,' by conjugation with motility-restricted bacteria, and finally mobilize towards a target point for delivery.

Item Type: Article
Additional Information: Funding Information: MAURO CONTI received the PhD degree from the Sapienza University of Rome, Italy, in 2009. He is full professor with the University of Padua, Italy, and affiliate professor with the University of Washington, Seattle. After his PhD, he was a post-doc researcher with Vrije Universiteit Amsterdam, the Netherlands. In 2011, he joined as an assistant professor with the University of Padua, where he became associate professor in 2015, and full profes-sor in 2018. He has been visiting researcher with GMU (2008, 2016), UCLA (2010), UCI (2012, 2013, 2014, 2017), TU Darmstadt (2013), UF (2015), and FIU (2015, 2016). He has been awarded with a Marie Curie Fellowship (2012) by the European Commission, and with a Fellowship by the German DAAD (2013). His research is also funded by companies, including Cisco and Intel. His main research interest include the area of security and privacy. In this area, he published more than 250 papers in topmost international peer-reviewed journals and conference. He is area editor-in-chief of the IEEE Communications Surveys & Tutorials, and associate editor for several journals, including the IEEE Communications Surveys & Tutorials, the IEEE Transactions on Information Forensics and Security, and the IEEE Transactions on Network and Service Management. He was program chair for TRUST 2015, ICISS 2016, WiSec 2017, and general chair for SecureComm 2012 and ACM SAC-MAT 2013. He is a senior member of the IEEE. Publisher Copyright: © 2013 IEEE.
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/1700/1701
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Depositing User: Admin SSL
Date Deposited: 19 Oct 2022 23:03
Last Modified: 15 Aug 2023 23:35
URI: http://repository-testing.wit.ie/id/eprint/3823

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