Macular carotenoids and age-related maculopathy

O'Connell, Eamonn and Neelam, Kumari and Nolan, John and Eong, Kah Guan Au and Beatty, Stephan (2006) Macular carotenoids and age-related maculopathy. Annals of the Academy of Medicine Singapore, 35 (11). pp. 821-830. ISSN 0304-4602

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Lutein (L) and zeaxanthin (Z) are concentrated at the macula, where they are collectively known as macular pigment (MP), and where they are believed to play a major role in protecting retinal tissues against oxidative stress. Whilst the exact pathogenesis of age-related maculopathy (ARM) remains unknown, the disruption of cellular processes by oxidative stress may play an important role. Manipulation of dietary intake of L and Z has been shown to augment MP, thereby raising hopes that dietary supplementation with these carotenoids might prevent, delay, or modify the course of ARM. This article discusses the scientific rationale supporting the hypothesis that L and Z are protective against ARM, and presents the recent evidence germane to this theory.

Item Type: Article
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/2700
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Depositing User: Admin SSL
Date Deposited: 19 Oct 2022 23:05
Last Modified: 10 Aug 2023 07:25

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