Development of contact lenses for ocular drug delivery

Phelan, David and Fitzhenry, Laurence and Coffey, Austin and McLoughlin, Peter (2013) Development of contact lenses for ocular drug delivery. In: Society of Plastics Engineers - EUROTECH 2013 :. Society of Plastics Engineers - EUROTECH 2013 . Society of Plastics Engineers, FRA, pp. 285-289. ISBN 9781632665324

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Abstract

This study focussed on the development of a manufacturing and characterisation process for the production of contact lenses with controlled release properties. Three lens compositions with varying degrees of cross-linking (CL) density were studied, A (2.7% w/w), B (3.8% w/w) and C (7.8% w/w) The formulations were studied to determine the effect of CL density on the loading of Vitamin E. Vitamin E was loaded into the three polymer compositions with increased capacity observed with decreasing cross-link density, (1.8, 1.6 and 1.1 mg of Vitamin E loaded per lens for A, B and C, respectively). Critically Vitamin E was not released from the loaded lenses.

Item Type:	Book Section
Uncontrolled Keywords:	/dk/atira/pure/subjectarea/asjc/1400/1405
Departments or Groups:
Depositing User:	Admin SSL
Date Deposited:	19 Oct 2022 23:14
Last Modified:	07 Feb 2023 00:04
URI:	http://repository-testing.wit.ie/id/eprint/4797

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