Clinical trials investigating the macular carotenoids

Sabour-Pickett, Sarah and Nolan, John M. and Beatty, Stephen (2013) Clinical trials investigating the macular carotenoids. In: Carotenoids and Retinal Disease :. CRC Press, pp. 75-91. ISBN 9781466502048

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Abstract

The anatomical (central retinal), biochemical (antioxidant), and optical (short-wavelength filtering) properties of macular pigment (MP) have generated interest in the biologically plausible rationale that MP may not only confer protection against age-related macular degeneration (AMD) but also optimize vision. The testing of this hypothesis has been a subject of growing interest over the past decade. This chapter reviews the evidence from the clinical trials that have investigated the role of macular carotenoid supplementation on macular pigment optical density (MPOD), on visual performance, and on the risk of disease progression in subjects afflicted with AMD. In addition, the more recent studies investigating the impact of supplementation with the macular carotenoids on visual performance in normal subjects (without disease) will be discussed.

Item Type: Book Section
Additional Information: Publisher Copyright: © 2014 by Taylor & Francis Group, LLC.
Uncontrolled Keywords: /dk/atira/pure/subjectarea/asjc/2700
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Depositing User: Admin SSL
Date Deposited: 19 Oct 2022 23:15
Last Modified: 07 Jun 2023 18:38
URI: http://repository-testing.wit.ie/id/eprint/4916

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