MiRNA biogenesis and regulation of diseases : An overview

Vishnoi, Anchal and Rani, Sweta (2017) MiRNA biogenesis and regulation of diseases : An overview. In: Methods in Molecular Biology :. Methods in Molecular Biology . Humana Press Inc., pp. 1-10.

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Abstract

MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to target mRNAs. Since it was discovered in 1993, miRNA are found in all eukaryotic cells conserved across the species. In recent years, regulation of miRNAs are extensively studied for their role in biological processes as well as in development and progression of various human diseases including retinal disorder, neurodegenerative diseases, cardiovascular disease and cancer. This chapter summarises miRNA biogenesis and explores their potential roles in a variety of diseases. miRNAs holds huge potential for diagnostic and prognostic biomarkers, and as predictors of drug response.

Item Type:	Book Section
Additional Information:	Publisher Copyright: © Springer Science+Business Media New York 2017.
Uncontrolled Keywords:	/dk/atira/pure/subjectarea/asjc/1300/1312
Departments or Groups:
Depositing User:	Admin SSL
Date Deposited:	19 Oct 2022 23:17
Last Modified:	11 Aug 2023 01:35
URI:	http://repository-testing.wit.ie/id/eprint/5117

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